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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX6
All Species:
13.33
Human Site:
Y398
Identified Species:
24.44
UniProt:
O95947
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95947
NP_004599.2
436
47045
Y398
H
G
S
G
G
S
G
Y
P
A
A
P
P
A
V
Chimpanzee
Pan troglodytes
XP_523337
436
47083
Y398
H
G
S
G
G
S
G
Y
P
A
A
P
P
A
V
Rhesus Macaque
Macaca mulatta
XP_001098963
496
53657
Y407
P
G
P
G
G
S
G
Y
P
A
A
P
P
A
A
Dog
Lupus familis
XP_547068
436
47185
Y398
P
G
P
G
G
S
G
Y
P
A
A
A
P
T
A
Cat
Felis silvestris
Mouse
Mus musculus
P70327
540
58610
S398
W
T
R
G
L
C
L
S
G
S
S
I
C
T
I
Rat
Rattus norvegicus
Q5I2P1
517
57726
G474
R
Q
C
G
P
Q
T
G
L
Q
S
P
G
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520749
277
31432
N248
F
A
K
G
F
R
E
N
G
R
N
C
K
R
E
Chicken
Gallus gallus
P79779
361
41167
F332
D
V
A
A
L
N
D
F
R
G
R
C
H
P
L
Frog
Xenopus laevis
Q8AV66
506
56540
S381
G
A
P
L
Q
M
S
S
Q
T
P
G
T
F
L
Zebra Danio
Brachydanio rerio
P79742
473
53459
P378
D
V
R
L
P
L
P
P
K
L
S
R
V
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
E648
L
Q
A
D
A
D
V
E
R
D
G
S
D
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
S391
V
E
A
T
S
E
D
S
E
E
A
E
K
P
E
Sea Urchin
Strong. purpuratus
XP_797010
645
70075
Q492
D
N
G
L
G
S
V
Q
P
A
T
A
L
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
81.8
90.1
N.A.
64.4
34.8
N.A.
43.8
35
43
37
N.A.
22.8
N.A.
35.5
30.2
Protein Similarity:
100
99
83.2
92.1
N.A.
67.9
48.5
N.A.
48.3
47.4
54.5
52.8
N.A.
30.7
N.A.
52.5
43.8
P-Site Identity:
100
100
80
66.6
N.A.
6.6
13.3
N.A.
6.6
0
0
0
N.A.
0
N.A.
6.6
40
P-Site Similarity:
100
100
80
66.6
N.A.
26.6
33.3
N.A.
6.6
26.6
6.6
13.3
N.A.
13.3
N.A.
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
24
8
8
0
0
0
0
39
39
16
0
31
16
% A
% Cys:
0
0
8
0
0
8
0
0
0
0
0
16
8
0
0
% C
% Asp:
24
0
0
8
0
8
16
0
0
8
0
0
8
0
0
% D
% Glu:
0
8
0
0
0
8
8
8
8
8
0
8
0
0
16
% E
% Phe:
8
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
8
31
8
54
39
0
31
8
16
8
8
8
8
0
0
% G
% His:
16
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
8
0
0
0
0
0
8
0
0
0
16
0
0
% K
% Leu:
8
0
0
24
16
8
8
0
8
8
0
0
8
0
31
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
8
0
0
8
0
0
0
0
% N
% Pro:
16
0
24
0
16
0
8
8
39
0
8
31
31
16
0
% P
% Gln:
0
16
0
0
8
8
0
8
8
8
0
0
0
8
0
% Q
% Arg:
8
0
16
0
0
8
0
0
16
8
8
8
0
8
0
% R
% Ser:
0
0
16
0
8
39
8
24
0
8
24
8
0
16
8
% S
% Thr:
0
8
0
8
0
0
8
0
0
8
8
0
8
16
0
% T
% Val:
8
16
0
0
0
0
16
0
0
0
0
0
8
0
24
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _